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Atopic dermatitis AD is a chronic eczematous dermatitis that has a high prevalence and diverse clinical features. Although several hypotheses about its multifactorial pathogenesis have been suggested, the cause is not yet fully understood. A better understanding of the clinical features may helpful inelucidating the pathogenesis of AD.
This retrospective study analyzed the questionnaires, medical charts, and laboratory examination results of 5, patients diagnosed with AD at a single tertiary hospital in Korea. The demographics, allergic comorbidities, family history, severity, and treatment experiences of the patients were analyzed. Most of the patients were adults, The mean eczema area and severity index EASI score was found to be The anatomical involvements were different among the age groups, with more involvements of the head and neck in adults.
The patients reported seasonal changes and stress as the factors that aggravated their symptoms the most. Topical steroids and oral cyclosporine were the most used medications at our clinic, whereas This analysis of 5, patients would lead to a better understanding of various subtypes and diverse clinical features of AD in Koreans.
Distinct characteristics were observed among different age groups; thus, treatment strategies may need to be differentiated accordingly. Atopic dermatitis AD is a chronic relapsing, severely pruritic, eczematous skin disease that may be accompanied by other allergic diseases, such as asthma and allergic rhinitis. Clinical features of AD are diverse, and this heterogeneity may be due to the multifactorial pathogenesis of the disease, in which defects of the skin barrier, environmental factors, and immunological dysregulation are involved.
Due to such complicated mechanisms of pathogenesis, clinical features of patients with AD are complex and may differ even within the same age group. We reviewed the medical records and laboratory data of 5, patients who initially visited the outpatient clinic at the department of dermatology and was diagnosed with AD between October and January The diagnosis of AD was made according to the diagnostic features of Korean diagnostic criteria for AD, 9 which were established on the basis on the guidelines of Hanifin and Rajka.